The presynaptic protein bassoon organizes synaptic vesicles into functional pools at glutamatergic synapses via regulation of presynaptic phosphorylation and cAMP homeostasis. This study further reveals that a CDK5/PDE4/cAMP axis controls neurotransmitter release.

New paper is online

https://www.embopress.org/doi/full/10.15252/embr.202153659

Burcu joined lab several weeks ago to work on the role of CtBP1 in neurodevelopment.

This Monday, Lena defended her thesis. Well done, Lena! Congratulations and all the best for all your future projects!

We are pleased to announce a release of nice study led by our collaborator Prof. Christian Müller. It was pleasure to contribute, thanks Christian!

Neutral sphingomyelinase mediates the co-morbidity trias of alcohol abuse, major depression and bone defects

On Monday, Debarpan defended his PhD. Congratulations. You did a great job and we are delighted to have you in the team!

Our study about regulation of synaptic vesicle recycling at excitatory synapses by Amyloid beta and alpha7 nicotinic acetylcholine receptors is online.

Congratulations Dani and thanks to the whole team!

We discussed this topic extensively at our symposium at the 14th meeting of German neuroscience society in the symposium S26  Regulation of synaptic vesicle recycling: from physiology to disease.

Our new study is online.

Yesterday, after the work, we took our backpacks and climbed over the hill to look over town of Erlangen. Then we spent nice evening in the beer-garden in Atzelsberg.

Today Daniela defended her thesis. Congratulations, Dani! You did a great job!

Zoicas et all described new mouse model of depression where acid sphyngomyelinase (Smpd1) was overexpressed exclusively in the forebrain. Thanks for nice collaboration Iulia and Cosima!